Searchable abstracts of presentations at key conferences in endocrinology

ea0063p60 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

Adrenal morphology in a large cohort of adult subjects with congenital adrenal hyperplasia due to 21-hydroxylase deficiency

Oriolo Claudia , Gasparini Daniela Ibarra , Altieri Paola , Ruffilli Francesca , Corzani Francesca , Dalmazi Guido Di , Vicennati Valentina , Pagotto Uberto , Gambineri Alessandra

Introduction: The adrenal morphology in congenital adrenal hyperplasia (CAH) is poorly described in the literature, so that adrenal radiological evaluation is not recommended in patients with CAH. The aim of this study was to evaluate the adrenal morphology in a large cohort of adult patients with CAH due to 21-hydroxylase deficiency and its correlation with the subtype of CAH (non-classical-NCAH, simple virilizing-SV, or salt wasting-SW), the hormonal status and the treatment...

ea0037ep867 | Thyroid cancer | ECE2015

The two tyrosine kinase inhibitors, CLM29 and CLM3, have antineoplastic activity in primary cultures from anaplastic thyroid cancer obtained from fine needle aspiration

Ferrari Silvia Martina , Fallahi Poupak , Motta Concettina La , Materazzi Gabriele , Ragusa Francesca , Limongi Francesca , Ruffilli Ilaria , Settimo Federico Da , Miccoli Paolo , Antonelli Alessandro

Anaplastic thyroid cancer (ATC) is one of the most lethal endocrine malignancy, with a mean survival of about 6 months. Until now, the most effective therapy for ATC comprises a multimodal treatment protocol, including surgery, chemotherapy (doxorubicin and cisplatin), and hyperfractionated accelerated external beam radiotherapy, with a median patient survival of 10 months. A possible increase in the effectiveness of the treatment could be achieved testing the sensitivity of &...